The GRK2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GRK2. This antibody recognizes Human, Mouse, and Rat antigen. The GRK2 Polyclonal Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner